Kidney Proximal Tubule Epithelial Cells. Human renal proximal tubule cells are isolated from the proximal tubule and are ideal for drug transporter studies. Proximal tubular epithelial cells ptecs have a pivotal role in kidney disease.
To address this we have created rptec drug transporter knockout ko models using compozr zinc finger nuclease zfn technology. However current methods for investigating drug transporter interactions involve inhibitors or knockdown methods that are often nonspecific or inefficient. Human renal proximal tubule cells are isolated from the proximal tubule and are ideal for drug transporter studies.
Human renal proximal tubule cells are isolated from the proximal tubule and are ideal for drug transporter studies.
Under normal circumstances more than two thirds of filtered salt and water and all filtered bicarbonate is reabsorbed in the proximal tubule. Under normal circumstances more than two thirds of filtered salt and water and all filtered bicarbonate is reabsorbed in the proximal tubule. Human renal proximal tubule cells are isolated from the proximal tubule and are ideal for drug transporter studies. The proximal tubules make up a significant portion of the kidneys.