Kidney Epithelial Cell Marker. Injury to labeled proximal tubule epithelia induced expression of cd24 cd133 vimentin and kidney injury molecule 1 markers of putative epithelial stem cells in the human kidney. Kidney cells podocytes glomerular basement membrane parietal epithelium mesangial cells glomerular endothelium macula densa tubule epithelium.
Most of them were cell culture studies 12 40 45 that clearly showed that renal tubular epithelial cells when exposed to profibrotic cytokines especially tgf β1 lose cell polarity downregulate epithelial markers e cadherin β catenin zonula occludens protein 1 acquire mesenchymal features become spindle shaped and mobile produce mmp 2 and express mesenchymal markers vimentin α sma. Injury to labeled proximal tubule epithelia induced expression of cd24 cd133 vimentin and kidney injury molecule 1 markers of putative epithelial stem cells in the human kidney. Kidney cells podocytes glomerular basement membrane parietal epithelium mesangial cells glomerular endothelium macula densa tubule epithelium.
Most of them were cell culture studies 12 40 45 that clearly showed that renal tubular epithelial cells when exposed to profibrotic cytokines especially tgf β1 lose cell polarity downregulate epithelial markers e cadherin β catenin zonula occludens protein 1 acquire mesenchymal features become spindle shaped and mobile produce mmp 2 and express mesenchymal markers vimentin α sma.
Similar results were observed in cultured proximal tubules in which labeled clones proliferated and expressed dedifferentiation and injury markers. Keratins are highly specific markers for epithelial cells and their loss was suggested as a characteristic finding of epithelial to mesenchymal transition and chronic kidney injury. Tubule epithelial cell markers clicking on a molecule name will take you to our selection of antibodies proteins small molecules immunoassays and enzymatic assays for that molecule. Most of them were cell culture studies 12 40 45 that clearly showed that renal tubular epithelial cells when exposed to profibrotic cytokines especially tgf β1 lose cell polarity downregulate epithelial markers e cadherin β catenin zonula occludens protein 1 acquire mesenchymal features become spindle shaped and mobile produce mmp 2 and express mesenchymal markers vimentin α sma.