Renal Failure Troponin Levels. 1 department of medicine university of toronto toronto ontario canada. Patients with renal dysfunction are known to exhibit an elevated risk of cardiovascular disease and more often present with atypical symptoms.
Elevations in tnt are predictors of increased mortality and worsening long term cardiovascular outcomes especially in the presence of known coronary artery disease. The presence of elevated levels of circulating troponins in patients with renal failure has been known for at least 15 years. 12 at one time it was considered that an elevation of troponin in a setting of decreased creatinine clearance was not of substantial diagnostic or prognostic importance.
12 the cause of stable troponin elevation in patients with ckd has been.
Patients with renal dysfunction are known to exhibit an elevated risk of cardiovascular disease and more often present with atypical symptoms. 12 the cause of stable troponin elevation in patients with ckd has been. Regardless of the cause studies have shown an increase in mortality in renal failure patients whose troponins are elevated. Advances in assay technology have since enabled troponin to be measured in the healthy population enabling better assessment of the factors influencing troponin concentrations.