Human Primary Kidney Epithelial Cells. Renal epithelial cells display a polarized morphology which is essential for their function. In order to investigate the molecular and cellular mechanisms underlying the pathophysiology of kidney injuries a stable and well characterized primary culture model of proximal tubular cells is required.
Ex Vivo Analysis Of Renal Proximal Tubular Cells Bmc Molecular And Cell Biology Full Text from bmcmolcellbiol.biomedcentral.com
Kidneys have a very complex structure and contain diverse epithelia such as those in the convoluted tubules the cortical collecting ducts the calyxes and the renal pelvis. Cultures are then expanded. The diverse functions of epithelial cells include protection absorption transcellular transport secretion and sensation.
Human primary renal epithelial cell culture system the epithelium is at the interface between the body of an organism and the external environment covering all exterior surfaces and interior lumina.
Human renal cortical cells hrce are from proximal and distal tubules. The adult kidney is composed of between 250 000 and 1 million nephrons made of specialized epithelial cells that form the bowman s capsule proximal and distal tubules and collecting ducts tisher and madsen 1986. Cultures are then expanded. Human mesangial cells hmc are isolated from the renal glomerulus and modified smooth muscle cells between capillaries.
