Epithelial Cells Kidney Fibrosis. However an increasing number of studies raise doubts about the existence of this process in vivo. Findings from an in vitro model abstract.
All cell types present in the kidney including epithelial cells endothelial cells mesangial cells as well as immune cells contribute to the progression of chronic kidney diseases. Kidney fibrosis a scarring of the tubulo interstitial space is due to activation of interstitial. In this review we shift this concept to renal tubules as a driving force in the progression of kidney disease.
In response to injury tubular epithelial cells tecs can synthesize and secrete varieties of bioactive molecules that drive interstitial inflammation and fibrosis.
In response to injury tubular epithelial cells tecs can synthesize and secrete varieties of bioactive molecules that drive interstitial inflammation and fibrosis. However an increasing number of studies raise doubts about the existence of this process in vivo. Theoretically among the various risk factors during the pathophysiology process of aki are a series of inflammatory responses such as epithelial cell apoptosis fibroblast proliferation and tubulointerstitial fibrosis which may subsequently lead to the development of ckd and kidney dysfunction 5 6. Kidney fibrosis a scarring of the tubulo interstitial space is due to activation of interstitial.